The current pace of data center development in the U.S. is unprecedented precedent in terms of announced expenditures and in breadth of geographical reach. Nearly every region of the country is seeing announcements of massive data center developments, creating significant economic opportunities while placing new strains on power, water, and wastewater systems. While power and water impacts are well understood, wastewater challenges vary significantly on the cooling system design. Cooling system selection for data centers alone can dramatically influence discharge volumes, chemical composition, and treatment requirements. Understanding these impacts helps municipal treatment facilities determine whether they can manage data center discharges within existing infrastructure or if modifications will be necessary. Discharges may contain scale reducers, corrosion inhibitors, and biocides, which can disrupt biological processes like nitrification, critical for meeting regulatory discharge requirements. Smaller municipal facilities may need process adjustments if data center flows dominate influent flows. Data center wastewater typically exhibits high total dissolved solids (TDS) and low biological demand (BOD), requiring careful evaluation to maintain compliance with community discharge permits A thorough understanding of these characteristics is essential before accepting additional flows to safeguard the integrity of existing treatment processes and permit compliance. At the same time, these unique characteristics can create opportunities for innovative reuse strategies. This presentation will feature case studies from several current projects demonstrating approaches different communities have taken to managing the effluent flows from different data centers and some of the drawbacks and lessons learned from these approaches. These approaches include one community that elected to use the data center effluent untreated as a supplement to irrigation water at a park, another community that has combined data center flows with other industrial users to provide a balanced treatment system, and another community that has elected to exclude data center flows from municipal treatment systems, resulting in the data center constructing a bespoke treatment system for managing their discharges. Additionally, the presentation will also introduce tools for rapidly analyzing treatment alternatives during the planning phase, when developers are evaluating multiple cooling system options. These tools will help facilities assess whether existing infrastructure can accommodate new waste streams and identify areas requiring additional attention.