Odor control in municipal sewer systems is a critical challenge for utilities seeking to maintain community satisfaction and regulatory compliance. This project focused on identifying the source of odors and evaluating mitigation methods within an urban combined sewer network, ultimately traced to a bourbon distillery. MSD’s mission and commitment to reduce odors required a multi-faceted approach combining innovative sampling techniques, advanced process modeling, and collaborative alternatives analysis. The investigation began with implementation of a novel sampling method, including continuous dissolved sulfide measurements that enabled accurate and continuous characterization of dissolved sulfide concentrations in situ. The team then completed comprehensive sewer process modeling and utilized the sampling data to validate the model predictions and pinpoint odor sources. The sewer process modeling led to an understanding of the sulfide generation and transport dynamics in this sewer under varying hydraulic and chemical conditions. This approach provided actionable data that confirmed the distillery’s discharge as the primary contributor to elevated sulfide levels and associated elevated odor emissions. Vapor phase hydrogen sulfide (H2S) concentrations were measured at greater than 1,000 parts per million (ppm) during the sampling effort. Another unique aspect of the project was the coordination among multiple odor experts engaged by MSD. Each consultant brought specialized expertise in odor chemistry, sewer operations, and mitigation technologies. Through structured collaboration and fact-based discussions, the team evaluated a range of alternatives, including chemical dosing strategies, vapor-phase treatment options, and process modifications at the distillery. The alternatives analysis considered the universe of possible solutions and balanced technical feasibility, cost-effectiveness, and long-term sustainability to identify the most practical solution for odor reduction. The outcome of this effort underscores the importance of integrating advanced modeling tools, innovative field sampling, and stakeholder collaboration in addressing complex odor issues. By confirming the odor source and aligning expert recommendations, the project has provided MSD with a clear, actionable path forward. Next steps include piloting the recommended mitigation strategy, monitoring its effectiveness through continued sulfide sampling, and refining the approach based on performance data to ensure sustainable control of odors from this sewer. This case study offers valuable insights for utilities and industrial partners seeking to manage odor challenges in sewer systems, particularly where high-strength industrial discharges are involved.