Wastewater residuals management is a major annual operation cost component for water resource recovery facilities (WRRFs). Anaerobic digestion technology is one of the established technologies used to reduce sludge volume while producing biogas, a renewable energy. Jacobs has developed an innovative technology called the Microbial Hydrolysis Process (MHP) which uses a hyperthermolic bacteria known as Caldicellulosiruptor bescii (CB) to enhance anaerobic digestion (AD) by increasing volatile solids reduction (VSR) and biogas production. Unlike pre-digestion hydrolysis, MHP feeds digestate to a 75°C tank populated with CB (Parry et al. 2022). This process has a hydraulic retention time of two days and hydrolyzes complex carbohydrates to volatile acids (VAs), which are then fed back into AD systems, where methanogens convert them into biogas. Jacobs has conducted laboratory and pilot scale studies of the MHP with AD with solids from four different water resource recovery facilities (WRRFs). These four studies have achieved consistent results that show: increased VSR, increased biogas production, and higher cake solids of the final product. For example, the addition of MHP to AD systems significantly improved performance in all trials, increasing VSR from a baseline of 58 to over 75%. The improvement is VSR primarily attributed to the hydrolysis of recalcitrant organics, such as cellulose and complex carbohydrates or polysaccharides, in the MHP reactor. This is supported by the rise in volatile acids concentrations from 500 mg/L upstream of the MHP reactor to 1500 mg/L in the MHP reactor. Jacobs’ MHP technology has demonstrated significant improvements to anaerobic digestion, offering the highest achievable VSR for municipal WRRF AD systems to date while also reducing pathogen levels and improving dewaterability. This results in substantial cost savings on biosolids management – a major interest for WRRFs. The impressive results of the MHP laboratory and pilot studies have led to the development of preliminary designs for several WRRFs in the US and a full-scale design ongoing for VandCenter Syd (VCS) in Denmark. This presentation will give an overview of the MHP technology, the configurations that have been piloted and the laboratory and pilot data conducted over the past few years. The presentation will show the significant improvement of VSR and overall benefits of using MHP to enhance anaerobic digestion process at WRRFs.